Finite-temperature sequence alignment.
نویسندگان
چکیده
We develop a statistical theory of probabilistic sequence alignments derived from a 'thermodynamic' partition function at finite temperature. Such alignments are a generalization of those obtained from information-theoretic approaches. Finite-temperature statistics can be used to characterize the significance of an alignment and the reliability of its single element pairs.
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ورودعنوان ژورنال:
- Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing
دوره شماره
صفحات -
تاریخ انتشار 2000